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Embryonal rhabdomyosarcoma


Source: http://en.wikipedia.org/wiki/Embryonal_rhabdomyosarcoma
Updated: 2017-05-11T03:29Z
Embryonal rhabdomyosarcoma
Classification and external resources
Specialty{{#statements:P1995}}
OMIM268210 180295
DiseasesDB1557
Patient UKEmbryonal rhabdomyosarcoma
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Embryonal rhabdomyosarcoma (ERMS) is a rare histological form of cancer of connective tissue wherein the mesenchymally-derived malignant cells resemble the primitive developing skeletal muscle of the embryo. It is the most common soft tissue sarcoma occurring in children.[1]

Classification

ERMS is the more common of two major subtypes of rhabdomyosarcoma, the other being alveolar rhabdomyosarcoma.

It has been informally classified as a "small round blue cell tumor"[1] because of the characteristic microscopic appearance of its cells after histological staining with hematoxylin and eosin.

Prognosis and survival

The prognosis for rhabdomyosarcoma has improved greatly in recent decades, with over 70% of patients surviving for five years after diagnosis.[2]

References

  1. ^ a b Masola V, Maran C, Tassone E, Zin A, Rosolen A, Onisto M (2009). "Heparanase activity in alveolar and embryonal rhabdomyosarcoma: implications for tumor invasion". BMC Cancer. 9: 304. PMC 2743710Freely accessible. PMID 19715595. doi:10.1186/1471-2407-9-304. 
  2. ^ Breitfeld PP, Meyer WH (August 2005). "Rhabdomyosarcoma: new windows of opportunity". Oncologist. 10 (7): 518–27. PMID 16079319. doi:10.1634/theoncologist.10-7-518. 
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