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Therapeutic ultrasound refers generally to any type of ultrasonic procedure that uses ultrasound for therapeutic benefit. Physiotherapeutic ultrasound was introduced into clinical practice in the 1950s, with lithotripsy introduced in the 1980s. Others are at various stages in transitioning from research to clinical use: HIFU, targeted ...
The therapeutic gene or drug of interest thus may translocate within the cell. Sonoporation, or cellular sonication, is the use of sound in the ultrasonic range for increasing the permeability of the cell plasma membrane. This technique is usually used in molecular biology and non-viral gene therapy in order to allow uptake of large molecules ...
Sonodynamic therapy (SDT) is a noninvasive treatment, often used for tumor irradiation, that utilizes a sonosensitizer and the deep penetration of ultrasound to treat lesions of varying depths by reducing target cell number and preventing future tumor growth. [1] [2] Many existing cancer treatment strategies cause systemic toxicity or cannot ...
Sonophoresis. Sonophoresis also known as phonophoresis, is a method that utilizes ultrasound to enhance the delivery of topical medications through the stratum corneum, to the epidermis and dermis. Sonophoresis allows for the enhancement of the permeability of the skin along with other modalities, such as iontophoresis, to deliver drugs with ...
Low-intensity pulsed ultrasound ( LIPUS) is a technology that can be used for therapeutic purposes. It exploits low intensity and pulsed mechanical waves in order to induce regenerative and anti-inflammatory effects on biological tissues, such as bone, [1] cartilage, and tendon. [2] Even if the real mechanism underlying its effectiveness has ...
Ultrasonic cavitation inception will occur when the acceleration of the ultrasound source is enough to produce the needed pressure drop. This pressure drop depends on the value of the acceleration and the size of the affected volume by the pressure wave. The dimensionless number that predicts ultrasonic cavitation is the Garcia-Atance number.
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