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Tetrahydrocannabinolic acid (THCA) synthase (full name Δ 1-tetrahydrocannabinolic acid synthase) is an enzyme responsible for catalyzing the formation of THCA from cannabigerolic acid (CBGA). THCA is the direct precursor of tetrahydrocannabinol (THC) , the principal psychoactive component of cannabis , which is produced from various strains of ...
The Endocannabinoid System (ECS) regulates many functions of the human body. The ECS plays an important role in multiple aspects of neural functions, including the control of movement and motor coordination, learning and memory, emotion and motivation, addictive-like behavior and pain modulation, among others.
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
THCa has a marginal difference in its chemical structure from regular THC, or delta-9, which is commonly known as marijuana, cannabis or weed. (Legal products that are marketed as delta-9 in Texas ...
Comparison of phytocannabinoids. Cannabinoids (/ kəˈnæbənɔɪdzˌ ˈkænəbənɔɪdz /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1][2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in ...
Cannabis has various mental and physical effects, which include euphoria, altered states of mind and sense of time, difficulty concentrating, impaired short-term memory, impaired body movement (balance and fine psychomotor control), relaxation, and an increase in appetite. Onset of effects is felt within minutes when smoked, but may take up to ...
THC is a lipophilic molecule [26] and may bind non-specifically to a variety of entities in the brain and body, such as adipose tissue (fat). [ 27 ] [ 28 ] THC, as well as other cannabinoids that contain a phenol group, possess mild antioxidant activity sufficient to protect neurons against oxidative stress , such as that produced by glutamate ...
11-Hydroxy-Δ9-tetrahydrocannabinol (11-OH-Δ9-THC, alternatively numbered as 7-OH-Δ1-THC), usually referred to as 11-hydroxy-THC is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after Δ 9 -THC is consumed. [ 1 ][ 2 ] After cannabis consumption, THC is metabolized inside the body by cytochrome P450 ...