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While uncommon in solid tumors, chromosomal translocations are a common cause of these diseases. This commonly leads to a different approach in diagnosis and treatment of hematological malignancies. Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology.
Cancer treatment needs to be selected to do least harm to both the woman and her embryo/fetus. In some cases a therapeutic abortion may be recommended. Radiation therapy is out of the question, and chemotherapy always poses the risk of miscarriage and congenital malformations. Little is known about the effects of medications on the child.
Response evaluation criteria in solid tumors ( RECIST) is a set of published rules that define when tumors in cancer patients improve ("respond"), stay the same ("stabilize"), or worsen ("progress") during treatment. The criteria were published in February 2000 by an international collaboration including the European Organisation for Research ...
Cyclophosphamide ( CP ), also known as cytophosphane among other names, [3] is a medication used as chemotherapy and to suppress the immune system. [4] As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. [4]
Targeted therapy. Patients and their diseases are profiled in order to identify the most effective treatment for their specific case. Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment ( pharmacotherapy) for cancer, [1] others being hormonal therapy and cytotoxic chemotherapy.
Multimodal cancer therapy. Multimodal cancer therapy, often referred to simply as multimodal therapy or multimodal cancer care, is an approach for treatment of cancer that combines radiation and chemotherapy [1] or other multiple therapeutic modalities. [1] [2] For example, in the case of mesotheliomas, treatments combine modalities such as ...
Tumor lysis syndrome. Tumor lysis syndrome ( TLS) is a group of metabolic abnormalities that can occur as a complication from the treatment of cancer, [1] where large amounts of tumor cells are killed off ( lysed) from the treatment, releasing their contents into the bloodstream. This occurs most commonly after the treatment of lymphomas and ...
An illustration depicting primary tumor (in the form of tumor microenvironment) and the circulating tumor cells. A circulating tumor cell ( CTC) is a cell that has shed into the vasculature or lymphatics [1] from a primary tumor and is carried around the body in the blood circulation. CTCs can extravasate and become seeds for the subsequent ...