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ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [1] [2] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. [3] [4] Improper ADP-ribosylation has been implicated in some forms of cancer. [5]
Daniel Atkinson (biochemist) Daniel Edward Atkinson (April 8, 1921 – February 2, 2024) was an American biochemist who worked at UCLA for 40 years from 1952 until his retirement in 1992, though he continued his scientific work as Emeritus Professor. [1] He is best known for the concept of energy charge.
Adenosine diphosphate receptor inhibitor. Adenosine diphosphate ( ADP) receptor inhibitors are a drug class of antiplatelet agents, used in the treatment of acute coronary syndrome (ACS) or in preventive treatment for patients who are in risk of thromboembolism, myocardial infarction or a stroke. These drugs antagonize the P2Y 12 platelet ...
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Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells. ADP consists of three important structural components: a sugar backbone attached to adenine and two phosphate groups bonded to the 5 carbon atom of ribose .
Adenosine diphosphate ribose (ADPR) is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. ADPR is created from cyclic ADP-ribose (cADPR) by the CD38 enzyme using nicotinamide adenine dinucleotide (NAD +) as a cofactor. ADPR binds to and activates the TRPM2 ion channel. ADPR is the most potent agonist of the TRPM2 ...
Carewise Health. Carewise Health, formerly SHPS, Inc. (pronounced "ships") is a national provider of health improvement programs. The company is headquartered in Louisville, Kentucky. Primary data center operations are in Minneapolis. Carewise Health has satellite offices in Minneapolis, Philadelphia, Scottsdale, Arizona, Seattle, and Walnut ...