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Erythropoietin (/ ɪ ˌ r ɪ θ r oʊ ˈ p ɔɪ. ɪ t ɪ n,-r ə-,-p ɔɪ ˈ ɛ t ɪ n,-ˈ iː t ɪ n /; EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.
e. The European Patent Office ( EPO) [notes 1] is one of the two organs of the European Patent Organisation (EPOrg), the other being the Administrative Council. [4] The EPO acts as executive body for the organisation [5] [6] while the Administrative Council acts as its supervisory body [5] as well as, to a limited extent, its legislative body.
Epoetin alfa is a human erythropoietin produced in cell culture using recombinant DNA technology. [6] Authorised by the European Medicines Agency on 28 August 2007, it stimulates erythropoiesis (increasing red blood cell levels) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy . Epoetin is ...
Erythropoietin receptor. The erythropoietin receptor ( EpoR) is a protein that in humans is encoded by the EPOR gene. [5] EpoR is a 52 kDa peptide with a single carbohydrate chain resulting in an approximately 56-57 kDa protein found on the surface of EPO responding cells. It is a member of the cytokine receptor family.
Donati felt this work "opened the road to EPO . . . because blood doping was a trial to understand the role of EPO". [36] Dr. Michele Ferrari , a former student and protege of Conconi, [37] had a controversial interview mentioning the drug in 1994, just after his Gewiss–Ballan team had a remarkable performance in the La Flèche Wallonne race.
Kill switch. A kill switch, also known more formally as an emergency brake, emergency stop ( E-stop ), emergency off ( EMO ), or emergency power off ( EPO ), is a safety mechanism used to shut off machinery in an emergency, when it cannot be shut down in the usual manner. Unlike a normal shut-down switch or shut-down procedure, which shuts down ...
e. In the United States, an exclusive provider organization ( EPO) is a hybrid health insurance plan in which a primary care provider is not necessary, but health care providers must be seen within a predetermined network. Out-of-network care is not provided, and visits require pre-authorization. Doctors are paid as a function of care provided ...
v. t. e. The European Patent Organisation (sometimes abbreviated EPOrg [1] in order to distinguish it from the European Patent Office, one of the two organs of the organisation [2]) is a public international organisation created in 1977 by its contracting states to grant patents in Europe under the European Patent Convention (EPC) of 1973.