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U.S. Route 52 (US 52) runs east–west across the southern part of the state of Ohio along the Ohio River, passing through or very near the cities and towns of Cincinnati, Portsmouth, and Ironton. For its first 19 miles (31 km) or so, the highway runs concurrently with Interstate 74 (I-74) and I-75 before it winds through downtown Cincinnati ...
U.S. Route 50 (US 50) runs east–west across the southern part of the state of Ohio, passing through Cincinnati, Chillicothe, and Athens. It is mainly a two-lane road except for the easternmost and westernmost parts. Near Athens it runs concurrently with State Route 32 (SR 32), a four-lane divided highway known as Corridor D, and from ...
In Ohio, the highway runs 194.27 miles (312.65 km) from the Ohio River in Cincinnati to the Michigan state line north of West Unity. US 127 runs south to north in Ohio's westernmost counties along the border of Indiana. The highway is a main route connecting many small towns, including eight county seats. The highway was first designated in 1926.
Interstate 75 (I-75) runs from Cincinnati to Toledo by way of Dayton in the US state of Ohio. The highway enters the state running concurrently with I-71 from Kentucky on the Brent Spence Bridge over the Ohio River and into the Bluegrass region. I-75 continues along the Mill Creek Expressway northward to the Butler County line just north of I ...
Ohio State Route 32. State Route 32 (SR 32), also known as the James A. Rhodes Appalachian Highway, [3] is a major east–west highway across the southern portion of the U.S. state of Ohio. It is the eighth longest state route in Ohio, spanning southern Ohio from Cincinnati to Belpre, across the Ohio River from Parkersburg, West Virginia.
U.S. Route 42 (US 42) is an east–west United States highway that runs southwest–northeast for 350 miles (560 km) from Louisville, Kentucky to Cleveland, Ohio.The route has several names including Pearl Road from Cleveland to Medina in Northeast Ohio, Reading Road in Cincinnati, Cincinnati and Lebanon Pike in southwestern Ohio and Brownsboro Road in Louisville.
State Route 104 (SR 104) is a north–south highway in Southern Ohio. Its southern terminus is at U.S. Route 23 (US 23) in Portsmouth, Ohio and its northern terminus is at US 33 in Columbus. The route passes through or close to the towns of Portsmouth, Waverly, Chillicothe, Grove City, and Columbus. From Waverly to Chillicothe, it overlaps US 23.
State Route 28 (SR 28) is an east–west state highway in the U.S. state of Ohio. Both of the route's termini are on U.S. Route 50 (US 50). Its western end is in Milford and its eastern end is near Chillicothe. The route has an interchange with Interstate 275 (I-275), and also intersects US 68 and US 62. The route was formerly signed as SR 27 ...
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