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The band was named after Calvin Johnson 's basement recording studio, Dub Narcotic. [1] The band and its members were all based in Olympia, Washington when they were active in the band. Dub Narcotic Sound System has toured in the United States, Japan, Canada and Europe with bands such as Built to Spill, Fugazi, and the Jon Spencer Blues Explosion.
1913: The American Medical Association created a propaganda department to outlaw health fraud and quackery. [6] In the same year, California outlawed cannabis. 1914: The first recorded instance of the United States enacting a ban on the domestic distribution of drugs is the Harrison Narcotic Act [7] of 1914.
184. The Convention on Psychotropic Substances of 1971 is a United Nations treaty designed to control psychoactive drugs such as amphetamine-type stimulants, barbiturates, benzodiazepines, and psychedelics signed in Vienna, Austria on 21 February 1971. The Single Convention on Narcotic Drugs of 1961 did not ban the many newly discovered ...
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic. It is 20 to 40 times more potent than heroin and 100 times more potent than morphine; [8] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. [9] [10] Fentanyl is also used as a sedative. [11]
A sedative or tranquilliser [note 1] is a substance that induces sedation by reducing irritability [1] or excitement. [2] They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA).
Pentazocine. Pentazocine, [3] sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain. It is believed to work by activating (agonizing) κ-opioid receptors (KOR) and μ-opioid receptors (MOR). As such it is called an opioid as it delivers its effects on pain by interacting with the opioid receptors.
Midazolam is a short-acting benzodiazepine in adults with an elimination half-life of 1.5–2.5 hours. [11] In the elderly, as well as young children and adolescents, the elimination half-life is longer. [41] [63] Midazolam is metabolised into an active metabolite alpha-hydroxymidazolam.
It is unclear if use is safe during pregnancy. [8] [13] Naltrexone is an opioid antagonist and works by blocking the effects of opioids, including both opioid drugs as well as opioids naturally produced in the brain. [8] Naltrexone was first made in 1965 and was approved for medical use in the United States in 1984.
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