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Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Its chemical formula C 21 H 30 O 2 includes compounds, the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ 9 ...
Cannabis. Cannabis, [a] also known as marijuana [b] or weed among other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries.
Medications containing natural or synthetic cannabinoids or cannabinoid analogs: Dronabinol (Marinol), is synthetic Δ 9-tetrahydrocannabinol (THC), used as an appetite stimulant, anti-emetic, and analgesic; Nabilone (Cesamet, Canemes), a synthetic cannabinoid and an analog of Marinol. It is Schedule II unlike Marinol, which is Schedule III
Most cannabis drug tests yield a positive result when the concentration of THC-COOH in urine exceeds 50 ng/mL. Urine testing is an immunoassay based test on the principle of competitive binding. Drugs which may be present in the urine specimen compete against their respective drug conjugate for binding sites on their specific antibody.
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis.. THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
THC further distributes into fatty tissues a few days after administration due to its high lipophilicity, and is found deposited in the spleen and fat after redistribution. Metabolism. Delta-9-THC is the primary molecule responsible for the effects of cannabis. Delta-9-THC is metabolized in the liver and turns into 11-OH-THC.
A dried cannabis flower. The effects of cannabis are caused by chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids such as tetrahydrocannabinol (THC) and 120 terpenes, which allow its drug to have various psychological and physiological effects on the human body.
Medical use is a common reason why people use marijuana. According to the National Institute on Drug Abuse, "The term medical marijuana refers to using the whole unprocessed marijuana plant or its basic extracts to treat a disease or symptom." However, the U.S. Food and Drug Administration (FDA) has not officially approved marijuana as a medicine.