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Half-life (symbol t½) is the time required for a quantity (of substance) to reduce to half of its initial value. The term is commonly used in nuclear physics to describe how quickly unstable atoms undergo radioactive decay or how long stable atoms survive. The term is also used more generally to characterize any type of exponential (or, rarely ...
Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (C max) to half of C max in the blood plasma.
Effective half-life. In pharmacokinetics, the effective half-life is the rate of accumulation or elimination of a biochemical or pharmacological substance in an organism; it is the analogue of biological half-life when the kinetics are governed by multiple independent mechanisms. This is seen when there are multiple mechanisms of elimination ...
Specific activity. In the context of radioactivity, activity or total activity (symbol A) is a physical quantity defined as the number of radioactive transformations per second that occur in a particular radionuclide. [1] The unit of activity is the becquerel (symbol Bq), which is defined equivalent to reciprocal seconds (symbol s -1 ).
Tritium (from Ancient Greek τρίτος (trítos) 'third') or hydrogen-3 (symbol T or 3 H) is a rare and radioactive isotope of hydrogen with half-life ~12.3 years. The nucleus of tritium (t, sometimes called a triton) contains one proton and two neutrons, whereas the nucleus of the common isotope hydrogen-1 (protium) contains one proton and zero neutrons, and that of a non-radioactive ...
Exponential decay. A quantity undergoing exponential decay. Larger decay constants make the quantity vanish much more rapidly. This plot shows decay for decay constant ( λ) of 25, 5, 1, 1/5, and 1/25 for x from 0 to 5. A quantity is subject to exponential decay if it decreases at a rate proportional to its current value.
Clearance (pharmacology) In pharmacology, clearance ( ) is a pharmacokinetic parameter representing the efficiency of drug elimination. This is the rate of elimination of a substance divided by its concentration. [1] The parameter also indicates the theoretical volume of plasma from which a substance would be completely removed per unit time.
Rubidium–strontium dating. The rubidium-strontium dating method (Rb-Sr) is a radiometric dating technique, used by scientists to determine the age of rocks and minerals from their content of specific isotopes of rubidium ( 87 Rb) and strontium ( 87 Sr, 86 Sr). One of the two naturally occurring isotopes of rubidium, 87 Rb, decays to 87 Sr ...