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Definition Positive predictive value (PPV) The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
Sensitivity (true positive rate) is the probability of a positive test result, conditioned on the individual truly being positive. Specificity (true negative rate) is the probability of a negative test result, conditioned on the individual truly being negative. If the true status of the condition cannot be known, sensitivity and specificity can ...
Prevalence is a term that means being widespread and it is distinct from incidence. Prevalence is a measurement of all individuals affected by the disease at a particular time, whereas incidence is a measurement of the number of new individuals who contract a disease during a particular period of time.
In fact, post-test probability, as estimated from the likelihood ratio and pre-test probability, is generally more accurate than if estimated from the positive predictive value of the test, if the tested individual has a different pre-test probability than what is the prevalence of that condition in the population. Example
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population . It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare.
Pre-test probability. The pre-test probability of an individual can be chosen as one of the following: The prevalence of the disease, which may have to be chosen if no other characteristic is known for the individual, or it can be chosen for ease of calculation even if other characteristics are known although such omission may cause inaccurate results
Forensic science. The discipline of forensic epidemiology (FE) is a hybrid of principles and practices common to both forensic medicine and epidemiology. FE is directed at filling the gap between clinical judgment and epidemiologic data for determinations of causality in civil lawsuits and criminal prosecution and defense.
The Positive predictive value (PPV) of a test is the proportion of persons who are actually positive out of all those testing positive, and can be calculated from a sample as: PPV = True positive / Tested positive. If sensitivity, specificity, and prevalence are known, PPV can be calculated using Bayes theorem.