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Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms [1] and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism ...
Toxicol. Sci. Toxicological Sciences is a monthly peer-reviewed scientific journal which covers all aspects of research on toxicology. It is published by Oxford University Press on behalf of the Society of Toxicology. It was established in 1981 as Fundamental and Applied Toxicology and obtained its current name in 1998.
Categories of organisms commonly used for assessing environmental toxicity. Environmental toxicology is a multidisciplinary field of science concerned with the study of the harmful effects of various chemical, biological and physical agents on living organisms. [1] [2] Ecotoxicology is a subdiscipline of environmental toxicology concerned with ...
Toxicology testing is commonly conducted during preclinical development for a substance intended for human exposure. Stages of in silico, in vitro and in vivo research are conducted to determine safe exposure doses in model organisms. If necessary, the next phase of research involves human toxicology testing during a first-in-man study.
Forensic toxicology. Forensic toxicology is a multidisciplinary field that combines the principles of toxicology with expertise in disciplines such as analytical chemistry, pharmacology and clinical chemistry to aid medical or legal investigation of death, poisoning, and drug use. [1] The paramount focus for forensic toxicology is not the legal ...
Interagency Center for the Evaluation of Alternative Toxicological Methods. Website. ntp .niehs .nih .gov. The National Toxicology Program ( NTP) is an inter-agency program run by the United States Department of Health and Human Services to coordinate, evaluate, and report on toxicology within public agencies. [1]
The discipline of evidence-based toxicology ( EBT) strives to transparently, consistently, and objectively assess available scientific evidence in order to answer questions in toxicology, [1] the study of the adverse effects of chemical, physical, or biological agents on living organisms and the environment, including the prevention and ...
Toxicogenomics is a subdiscipline of pharmacology that deals with the collection, interpretation, and storage of information about gene and protein activity within a particular cell or tissue of an organism in response to exposure to toxic substances. Toxicogenomics combines toxicology with genomics or other high-throughput molecular profiling ...