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Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [10] the term was adopted by the American ...
Depression is a mental state of low mood and aversion to activity. [3] It affects more than 280 million people of all ages (about 3.5% of the global population). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5] Depressed people often experience loss of motivation or interest in, or reduced pleasure or ...
Five stages of grief. According to the model of the five stages of grief, or the Kübler-Ross model, those experiencing grief go through five emotions: denial, anger, bargaining, depression and acceptance. Although it is in common use, studies have not confirmed these stages, and the model has been criticized as outdated [1] as well as ...
The Great Depression (1929–1939) was a severe global economic downturn that affected many countries across the world. It became evident after a sharp decline in stock prices in the United States, leading to a period of economic depression. [1] The economic contagion began around September 1929 and led to the Wall Street stock market crash of ...
The ICD-11 of the World Health Organization (WHO) describes occupational burnout as an occupational phenomenon resulting from chronic workplace stress that hasn't been successfully managed, with symptoms characterized by "feelings of energy depletion or exhaustion; increased mental distance from one’s job, or feelings of negativism or cynicism related to one's job; and reduced professional ...
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [1] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
The Wall Street Crash of 1929 is often cited as the beginning of the Great Depression. It began on October 24, 1929, and kept going down until March 1933. It was the longest and most devastating stock market crash in the history of the United States. Much of the stock market crash can be attributed to exuberance and false expectations.
In the mid-20th century, researchers theorized that depression was caused by a chemical imbalance in neurotransmitters in the brain, a theory based on observations made in the 1950s of the effects of reserpine and isoniazid in altering monoamine neurotransmitter levels and affecting depressive symptoms. [32]
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