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In 1961, the company changed its name to Automatic Data Processing, Inc. (ADP), and began using punched card machines, check printing machines, and mainframe computers. ADP went public in 1961 with 300 clients, 125 employees, and revenues of approximately US$400,000. [3] The company established a subsidiary in the United Kingdom in 1965.
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Henry Taub (September 20, 1927 – March 31, 2011) [1] was an American businessman and philanthropist of Hungarian-Jewish descent who was a co-founder of ADP. Raised in Paterson, New Jersey, Taub attended Eastside High School. [2] Taub was educated at New York University. He graduated from NYU in 1947 with a degree in accounting. [3]
1993: split to create 905. 2001: overlaid by 647. 2013: overlaid by 437. 2025: overlaid by 942. area code 387 is reserved as a fifth code for the region. 417. Missouri (Springfield, Joplin, Branson, Lamar, Lebanon, and most of southwestern Missouri) 1950. created from parts of the area codes 314 and 816.
ADP-ribose. ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. [ 1 ][ 2 ] It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. [ 3 ][ 4 ] Improper ADP-ribosylation has been implicated in some forms of ...
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Once PARP detects a SSB, it binds to the DNA, undergoes a structural change, and begins the synthesis of a polymeric adenosine diphosphate ribose (poly (ADP-ribose) or PAR) chain, which acts as a signal for the other DNA-repairing enzymes. Target enzymes include DNA ligase III (LigIII), DNA polymerase beta (polβ), and scaffolding proteins such ...