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Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
Septic shock is a potentially fatal medical condition that occurs when sepsis, which is organ injury or damage in response to infection, leads to dangerously low blood pressure and abnormalities in cellular metabolism. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defines septic shock as a subset of sepsis ...
Acute kidney injury, shock, septic shock, sepsis, multiple organ failure. In immunology, systemic inflammatory response syndrome ( SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it ...
Multiple organ dysfunction syndrome (MODS) is altered organ function in an acutely ill patient requiring medical intervention to achieve homeostasis.Although Irwin and Rippe cautioned in 2005 that the use of "multiple organ failure" or "multisystem organ failure" should be avoided, both Harrison's (2015) and Cecil's (2012) medical textbooks still use the terms "multi-organ failure" and ...
Medical use. The SOFA scoring system is useful in predicting the clinical outcomes of critically ill patients. According to an observational study at an Intensive Care Unit (ICU) in Belgium, the mortality rate is at least 50% when the score is increased, regardless of initial score, in the first 96 hours of admission, 27% to 35% if the score remains unchanged, and less than 27% if the score is ...
Distributive shock. Distributive shock is a medical condition in which abnormal distribution of blood flow in the smallest blood vessels results in inadequate supply of blood to the body's tissues and organs. [1] [2] It is one of four categories of shock, a condition where there is not enough oxygen -carrying blood to meet the metabolic needs ...
The Sepsis Six is the name given to a bundle of medical therapies designed to reduce mortality in patients with sepsis. [citation needed] Drawn from international guidelines that emerged from the Surviving Sepsis Campaign [1] [2] the Sepsis Six was developed by The UK Sepsis Trust. [3] (. Daniels, Nutbeam, Laver) in 2006 as a practical tool to ...
Neonatal sepsis. Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".