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Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [1] [2] A minority of cancers are due to inherited genetic mutations. [3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [4]
Tobacco smoke, for example, causes 90% of lung cancer. Tobacco use can cause cancer throughout the body including in the mouth and throat, larynx, esophagus, stomach, bladder, kidney, cervix, colon/rectum, liver and pancreas. Tobacco smoke contains over fifty known carcinogens, including nitrosamines and polycyclic aromatic hydrocarbons.
Breast cancer. Breast cancer is the most commonly diagnosed cancer among U.S. women. The ACS reports that 1 in 8 women will be diagnosed with invasive breast cancer in their lifetime, and 1 in 39 ...
World-wide, liver cancer is the 4th most frequent cause of cancer mortality, causing 9% of all cancer mortality (total liver cancer deaths in 2015 being 810,500), and coming, in frequency, after lung, colorectal and stomach cancers.
Carcinogenic bacteria. Cancer bacteria are bacteria infectious organisms that are known or suspected to cause cancer. [1] While cancer-associated bacteria have long been considered to be opportunistic (i.e., infecting healthy tissues after cancer has already established itself), there is some evidence that bacteria may be directly carcinogenic ...
Lung cancer. Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
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