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Portal. (video game) Portal is a 2007 puzzle - platform game developed and published by Valve. It was released in a bundle, The Orange Box, for Windows, Xbox 360 and PlayStation 3, and has been since ported to other systems, including Mac OS X, Linux, Android (via Nvidia Shield ), and Nintendo Switch .
Portal is a series of first-person puzzle-platform video games developed by Valve.Set in the Half-Life universe, the two main games in the series, Portal (2007) and Portal 2 (2011), center on a woman, Chell, forced to undergo a series of tests within the Aperture Science Enrichment Center by a malicious artificial intelligence, GLaDOS, that controls the facility.
Crystal structure of Akt-2-inhibitor complexes. [2] Protein kinase B ( PKB ), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration .
Physiologically based pharmacokinetic (PBPK) modeling is a mathematical modeling technique for predicting the absorption, distribution, metabolism and excretion (ADME) of synthetic or natural chemical substances in humans and other animal species. PBPK modeling is used in pharmaceutical research and drug development, and in health risk ...
Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ( phosphatidylinositol 3-kinase) and Akt ( protein kinase B ). Initial stimulation by one of the growth factors causes ...
Consumer Banking. Corporate Banking. Investment Banking. Website. pkb .gov .bd. Probashi Kallyan Bank is a state-owned bank in Bangladesh, a specialized financial institution for non-resident Bangladeshis. [1] [2] [3]
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PDPK1 is a master kinase, which is crucial for the activation of AKT /PKB and many other AGC kinases including PKC, S6K, SGK. An important role for PDPK1 is in the signaling pathways activated by several growth factors and hormones including insulin signaling. Mice lacking PDPK1 die during early embryonic development, indicating that this ...