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Plasminogen, sold under the brand name Ryplazim, is a biologic medication for the treatment of hypoplasminogenemia (plasminogen deficiency type 1). [1] [2] [3] It is purified from human plasma [1] [2] and is administered intravenously .
Hypoplasminogenemia. Hypoplasminogenemia, also known as plasminogen deficiency type 1, is a genetic disorder characterized by a lack of the protein plasminogen, which is responsible for the ability of the body to break down fibrin clots. [1] Plasminogen deficiency leads to an accumulation of fibrin, causing the development of growths (lesions ...
Emergent BioSolutions Inc. Emergent BioSolutions Inc. is an American multinational specialty biopharmaceutical company headquartered in Gaithersburg, Maryland. [2] It develops vaccines and antibody therapeutics for infectious diseases and opioid overdoses, and it provides medical devices for biodefense purposes.