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"The marketers of Prevagen preyed on the fears of older consumers experiencing age-related memory loss," said Jessica Rich, director of the FTC's Bureau of Consumer Protection, in a statement ...
Aequorin is a calcium-activated photoprotein isolated from the hydrozoan Aequorea victoria. [1] Its bioluminescence was studied decades before the protein was isolated from the animal by Osamu Shimomura in 1962. [2] In the animal, the protein occurs together with the green fluorescent protein to produce green light by resonant energy transfer ...
This is to say, apoaequorin is the enzyme produced in the photocytes of the animal, and coelenterazine is the substrate whose oxidation the enzyme catalyzes. When coelenterazine is bound, it is called aequorin. Notably, the protein contains three EF hand motifs that function as binding sites for Ca2+ ions.
Mayo Clinic (/ ˈ m eɪ j oʊ /) is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 7,300 physicians and scientists, along with another 66,000 administrative and allied health staff, across three major campuses: Rochester, Minnesota; Jacksonville, Florida; and Phoenix/Scottsdale, Arizona.
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Mayo v. Prometheus, 566 U.S. 66 (2012), was a case decided by the Supreme Court of the United States that unanimously held that claims directed to a method of giving a drug to a patient, measuring metabolites of that drug, and with a known threshold for efficacy in mind, deciding whether to increase or decrease the dosage of the drug, were not patent-eligible subject matter.
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