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Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ( phosphatidylinositol 3-kinase) and Akt ( protein kinase B ). Initial stimulation by one of the growth factors causes ...
Crystal structure of Akt-2-inhibitor complexes. [2] Protein kinase B ( PKB ), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration .
2-letter codes used by the United States Coast Guard (bold red text shows differences between ANSI and USCG) Abbreviations: GPO. Older variable-length official US Government Printing Office abbreviations. AP. Abbreviations from the AP Stylebook (bold red text shows differences between GPO and AP) Name and status of region. ISO.
e. In chemistry, an acid dissociation constant (also known as acidity constant, or acid-ionization constant; denoted ) is a quantitative measure of the strength of an acid in solution. It is the equilibrium constant for a chemical reaction. known as dissociation in the context of acid–base reactions.
Gross domestic product (GDP) is the market value of all final goods and services from a nation in a given year. [2] Countries are sorted by nominal GDP estimates from financial and statistical institutions, which are calculated at market or government official exchange rates. Nominal GDP does not take into account differences in the cost of ...
New Kids on the Block (also initialized as NKOTB) is an American boy band from Dorchester, Massachusetts. The band consists of brothers Jonathan and Jordan Knight, Joey McIntyre, Donnie Wahlberg, and Danny Wood. New Kids on the Block enjoyed success in the late 1980s and early 1990s and have sold more than 80 million records worldwide, and are ...
Activating transcription factor. Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. [1] First, they have been described as members of the CREB/ATF family, [2] whereas it turned out later that some of them might be more similar to AP-1 -like ...
PRKACB. cAMP-dependent protein kinase catalytic subunit beta is an enzyme that in humans is encoded by the PRKACB gene. [5] cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins.