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  2. Metabolic engineering - Wikipedia

    en.wikipedia.org/wiki/Metabolic_engineering

    Metabolic engineering specifically seeks to mathematically model these networks, calculate a yield of useful products, and pin point parts of the network that constrain the production of these products. Genetic engineering techniques can then be used to modify the network in order to relieve these constraints. Once again this modified network ...

  3. Ecological efficiency - Wikipedia

    en.wikipedia.org/wiki/Ecological_efficiency

    Ecological efficiency is a combination of several related efficiencies that describe resource utilization and the extent to which resources are converted into biomass. [1] Exploitation efficiency is the amount of food ingested divided by the amount of prey production ( ) Assimilation efficiency is the amount of assimilation divided by the ...

  4. Transformation efficiency - Wikipedia

    en.wikipedia.org/wiki/Transformation_efficiency

    In molecular biology, transformation efficiency is a crucial parameter, it is used to evaluate the ability of different methods to introduce plasmid DNA into cells and to compare the efficiency of different plasmid, vectors and host cells. This efficiency can be affected by a number of factors, including the method used for introducing the DNA ...

  5. Genotype frequency - Wikipedia

    en.wikipedia.org/wiki/Genotype_frequency

    Genotype frequency in a population is the number of individuals with a given genotype divided by the total number of individuals in the population. [2] In population genetics, the genotype frequency is the frequency or proportion (i.e., 0 < f < 1) of genotypes in a population. Although allele and genotype frequencies are related, it is ...

  6. BLOSUM - Wikipedia

    en.wikipedia.org/wiki/BLOSUM

    Positive and zero values have been highlighted. In bioinformatics, the BLOSUM ( BLO cks SU bstitution M atrix) matrix is a substitution matrix used for sequence alignment of proteins. BLOSUM matrices are used to score alignments between evolutionarily divergent protein sequences. They are based on local alignments.

  7. IC50 - Wikipedia

    en.wikipedia.org/wiki/IC50

    Half maximal inhibitory concentration ( IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or biological component by 50%. [1]

  8. Fixation index - Wikipedia

    en.wikipedia.org/wiki/Fixation_index

    The fixation index ( FST) is a measure of population differentiation due to genetic structure. It is frequently estimated from genetic polymorphism data, such as single-nucleotide polymorphisms (SNP) or microsatellites. Developed as a special case of Wright's F-statistics, it is one of the most commonly used statistics in population genetics.

  9. Rate of evolution - Wikipedia

    en.wikipedia.org/wiki/Rate_of_evolution

    Rate of evolution. The rate of evolution is quantified as the speed of genetic or morphological change in a lineage over a period of time. The speed at which a molecular entity (such as a protein, gene, etc.) evolves is of considerable interest in evolutionary biology since determining the evolutionary rate is the first step in characterizing ...