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Human leukocyte antigen. The human leukocyte antigen ( HLA) system or complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]
Alpha toxin from S. aureus ( PDB: 7ahl ). Alpha-toxin, also known as alpha-hemolysin (Hla), is the major cytotoxic agent released by bacterium Staphylococcus aureus and the first identified member of the pore forming beta-barrel toxin family. [1] This toxin consists mostly of beta-sheets (68%) with only about 10% alpha-helices.
HLA-NET is a network targeted to the study of Human leukocyte antigen (HLA) from a populational point of view. The network was initiated by COST Action BM0803 [1] in January 2009. Currently HLA-NET activities are being coordinated by a subcommittee of the scientific committee of the European Federation for Immunogenetics .
The HLA Informatics Group ( HIG) is a research group led by Professor Steven Marsh at the Anthony Nolan Research Institute that develops, runs and maintains the IMGT ( immunogenetics )/HLA ( Human leukocyte antigen) Database and the IPD (immuno polymorphism database). The IMGT/HLA database originated as part of IMGT and was merged with IPD in ...
Histocompatibility. Histocompatibility, or tissue compatibility, is the property of having the same, or sufficiently similar, alleles of a set of genes called human leukocyte antigens (HLA), or major histocompatibility complex (MHC). [1] Each individual expresses many unique HLA proteins on the surface of their cells, which signal to the immune ...
1w0w , 1uxw , 1of2 , 1k5n . Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) [1] is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. HLA-B27 is strongly associated with ankylosing ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human major histocompatibility complex, class II, DP alpha 1 Identifiers Symbol HLA-DPA1 Alt. symbols HLA-DP1A NCBI gene 3113 HGNC 4938 OMIM 142880 RefSeq NM_033554 UniProt P20036 Other data Locus Chr. 6 p21.3 Search for Structures Swiss-model ...
HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene. [4] HLA-DRA encodes the alpha subunit of HLA-DR. Unlike the alpha chains of other Human MHC class II molecules, the alpha subunit is practically invariable. However it can pair with, in any individual, the beta chain from 3 ...