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Semaglutide is an antidiabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management. [19] [20] [21] It is a peptide similar to the hormone glucagon-like peptide-1 (GLP-1), modified with a side chain .
They added that semaglutide drugs seemed to promote better overall cardiovascular health as well. Semaglutide — a glucagon-like peptide-1 (GLP-1) receptor agonist found in medications such as ...
The company in March reported that the diabetes drug known chemically as semaglutide cut the combined risk of kidney complications and cardiovascular events by 24% over the next 3.4 years in ...
The company’s oral medication kits start at $79 a month, and its compounded GLP-1 injections will start at $199 a month. Even before it added compounded GLP-1s to its portfolio, Hims & Hers said ...
HbA1c was significantly improved compared to cagrilintide alone and non-significantly better than semaglutide alone. In a Phase II trial, weight loss averaged -15.6 percent after 32 weeks, making CagriSema comparable in efficacy to tirzepatide. A future trial sponsored by Novo Nordisk is comparing tirzepatide and CagriSema head-to-head.
Attempts to develop an orally bioavailable GLP-1 agonist, either a modified peptide, as in the case of oral semaglutide, or a small molecule drug have produced additional drug candidates. Other companies have tested inhaled or transdermal administration. Cost. GLP-1 agonists are more expensive than other treatments for type 2 diabetes.
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