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  2. Integrated stress response - Wikipedia

    The integrated stress response is a cellular stress response conserved in eukaryotic cells that downregulates protein synthesis and upregulates specific genes in response to internal or environmental stresses. [1] Contents 1 Background 2 eIF2 protein complex 3 Protein kinases 3.1 PERK 3.2 HRI 3.3 GCN2 3.4 PKR 4 ATF4

  3. Chronic stress - Wikipedia

    Stress has a role in humans as a method of reacting to difficult and possibly dangerous situations. The "fight or flight" response when one perceives a threat helps the body exert energy to fight or run away to live another day.

  4. Stress (biology) - Wikipedia

    Stress is the body's method of reacting to a condition such as a threat, challenge or physical and psychological barrier. There are two hormones that an individual produces during a stressful situation, these are well known as adrenaline and cortisol. [2] There are two kinds of stress hormone levels.

  5. Fight-or-flight response - Wikipedia

    The fight-or-flight or the fight-flight-or-freeze response (also called hyperarousal or the acute stress response) is a physiological reaction that occurs in response to a perceived harmful event, attack, or threat to survival. [1] It was first described by Walter Bradford Cannon. [a] [2] His theory states that animals react to threats with a ...

  6. Hans Selye - Wikipedia

    Hans Selye. János Hugo Bruno " Hans " Selye CC ( / ˈsɛljeɪ / [dubious – discuss]; Hungarian: Selye János Hungarian pronunciation: [ˈʃɛjɛ]; January 26, 1907 – October 16, 1982) was a pioneering Hungarian-Canadian endocrinologist who conducted important scientific work on the hypothetical non-specific response of an organism to ...

  7. Protection motivation theory - Wikipedia

    Protection motivation theory (PMT) was originally created to help understand individual human responses to fear appeals. Protection motivation theory proposes that people protect themselves based on two factors: threat appraisal and coping appraisal. Threat appraisal assesses the severity of the situation and examines how serious the situation ...

  8. Stimulus–response model - Wikipedia–response_model

    The stimulus–response model is a characterization of a statistical unit (such as a neuron ). The model allows the prediction of a quantitative response to a quantitative stimulus, for example one administered by a researcher. In psychology, stimulus response theory concerns forms of classical conditioning in which a stimulus becomes paired ...